Harley Street, Marylebone, W1G

Property Summary

This distinguished circa-1820 Grade II Listed building occupies a commanding position on Harley Street, one of London’s most internationally recognised addresses. Arranged over lower ground, ground and four upper floors, the property extends to approximately 10,348 sq ft and is offered as a freehold with full vacant possession, together with an adjoining mews property. Currently undergoing a comprehensive refurbishment programme, the building can be delivered fully completed with scope for bespoke customisation to suit an incoming purchaser’s precise requirements. The property retains its original mixed-use designation, incorporating four residential flats and licensing for up to fourteen medical practitioners, presenting a versatile proposition for private owner-occupiers, investors or medical operators seeking a flagship central London headquarters.

Key Features

• Grade II Listed mixed-use building constructed circa 1820
• Approximately 10,348 sq ft arranged over six floors
• Prime Harley Street freehold with full vacant possession
• Adjoining mews property included in the sale
• Comprehensive refurbishment programme currently underway with bespoke completion available
• Four residential flats within the building
• Licensed for up to 14 medical practitioners
• Passenger lift serving all floors
• Channelled stucco detailing to the ground floor façade
• Elegant double-panelled entrance doors
• Ornate period fireplaces and decorative ceiling cornices
• Exceptionally generous room proportions throughout
• Substantial three-phase 400W electricity supply
• EPC Rating C and D
• Westminster Council Tax Band G

Design Comment

Harley Street has long represented the gold standard of London’s medical and professional quarters, and this circa-1820 building embodies the scale and gravitas of the street’s earliest architecture. The retention of channelled stucco work, ornate fireplaces and decorative cornicing across six floors provides a rich heritage canvas that rewards considered, sensitive design. The inclusion of an adjoining mews property further extends the spatial and programmatic possibilities, offering scope for a self-contained residential annexe, staff quarters or ancillary accommodation that complements the principal building.

With the property already in the midst of a comprehensive refurbishment, there is a rare window for an incoming purchaser to direct the final specification — from material palettes and joinery profiles to bathroom and kitchen installations — ensuring every element aligns with a singular design vision. The passenger lift and substantial electrical infrastructure indicate a building that has already been adapted for modern performance; a thoughtful interior scheme can build upon these upgrades to introduce integrated climate control, advanced lighting design and discreet technology throughout, all while preserving the generous Georgian proportions that define each floor.

For a purchaser envisaging a flagship private medical practice combined with refined residential living, the dual-use designation presents an exceptional brief. Ground and lower-ground floors lend themselves to reception, consultation and treatment spaces finished to the highest clinical and aesthetic standards, while the upper floors can be reimagined as a substantial private apartment or collection of residences with interiors that honour the building’s listed character. Janine Stone & Co. would relish the opportunity to guide both the architectural detailing and the interior narrative of a project of this calibre.

Development Consultations

To assist potential buyers of this property to understand their full design and development options, Janine Stone & Co. is able to provide complimentary design concept and development consultations. It can be arranged for these consultations to take place at the property or in our London studio. Janine Stone & Co. will provide guidance on architecture, refurbishment and planning considerations, in addition to helping interested parties to develop their early design ideas into floor plans with estimated project costs and timelines for realisation.

Should a successful acquisition take place, we would be happy to take these initial concepts through to a full concept and subsequent planning, design and build phases.